Tangram Therapeutics PLC

Active04304473 Public limited company

Incorporated: 15 October 2001 (25 years)
Previously known as: E-Therapeutics PLC (until 18 September 2025)
Inrotis Technologies Limited (until 21 September 2007)
E-Therapeutic Systems Limited (until 18 March 2003)
Earlier: Crossco (643) Limited
Industry: Other research and experimental development on natural sciences and engineering (72190)
Directors: Laura Roca Alonso
Jeremy Punnett
David Gifford Leathes Prior
all 5 directors
Accounts type: Full
Region: Greater London
Address: 4 Kingdom Street
London
W2 6BD

Website & contact details

Group website: tangramtherapeutics.co.uk
The site of this company’s group or brand.

Filing status

Accounts due: 31 July 2027
Last accounts: 31 January 2026
Conf. stmt due: 29 October 2027
Last conf. stmt: 15 October 2026

Charges

Total: 2
Outstanding: 1
Part satisfied: 0
Satisfied: 1

Officers 6 active

Officer details are public data from the Companies House register.

Roca Alonso, Laura

Director · Appointed 30 September 2026

Spanish

Born February 1987 (39)

Punnett, Jeremy

Director · Appointed 16 July 2024

British,New Zealander

Born September 1973 (53)

Prior, David Gifford Leathes, Lord

Director · Appointed 23 May 2024

Also at Swannington Enterprises Limited, Lazard & Co., Services Limited, Lazard & Co., Limited · more companies

British

Born December 1954 (71)

Bretherton, Tim

Secretary · Appointed 25 November 2022

Bretherton, Michael Anthony

Director · Appointed 10 February 2020

British

Born December 1955 (70)

Jones, Trevor

Director · Appointed 28 October 2015

British

Born August 1942 (84)

Officer history (24 former)

30 September 2026

Appointed Roca Alonso, Laura as Director

30 March 2026

Resigned Mortazavi, Ahmad Ali as Director

16 July 2024

Appointed Punnett, Jeremy as Director

23 May 2024

Appointed Prior, David Gifford Leathes, Lord as Director

25 November 2022

Appointed Bretherton, Tim as Secretary

25 November 2022

Resigned Vistra Company Secretaries Limited as Corporate Secretary

1 August 2021

Appointed Vistra Company Secretaries Limited as Corporate Secretary

31 July 2021

Resigned Clare, Sarah Collette as Secretary

28 February 2020

Resigned Steven, Susan Margaret as Secretary

28 February 2020

Appointed Clare, Sarah Collette as Secretary

10 February 2020

Appointed Bretherton, Michael Anthony as Director

10 February 2020

Appointed Mortazavi, Ahmad Ali as Director

10 February 2020

Resigned Soden, Christine as Director

10 February 2020

Resigned Barlow, Raymond John as Director

10 February 2020

Resigned Medlicott, Steven as Director

10 February 2020

Resigned Ross, Iain Gladstone as Director

1 November 2017

Appointed Soden, Christine as Director

1 November 2017

Resigned Hoy, Bradley Richard as Director

6 April 2017

Appointed Barlow, Raymond John as Director

15 March 2017

Appointed Steven, Susan Margaret as Secretary

28 February 2017

Resigned Nicolson, Sean as Director

28 February 2017

Resigned Nicolson, Sean Torquil as Secretary

30 September 2016

Resigned Self, Stephen Raymond as Director

12 July 2016

Resigned Young, Malcolm Philip as Director

6 January 2016

Appointed Ross, Iain Gladstone as Director

28 October 2015

Resigned Chopra, Rajesh, Dr as Director

28 October 2015

Appointed Jones, Trevor as Director

1 April 2015

Appointed Nicolson, Sean as Director

31 December 2014

Resigned James, Oliver Francis Wintour, Professor as Director

7 April 2014

Resigned Elger, Daniel William, Dr as Director

7 April 2014

Appointed Medlicott, Steven as Director

3 February 2012

Appointed Chopra, Rajesh, Dr as Director

10 June 2011

Appointed Elger, Daniel William, Dr as Director

10 June 2011

Resigned Cordiner, Johnny Mark as Director

3 December 2010

Appointed Self, Stephen Raymond as Director

8 September 2010

Resigned Drucker, Royston Frederick, Dr as Director

4 September 2008

Appointed Hoy, Bradley Richard as Director

5 October 2007

Appointed James, Oliver Francis Wintour, Professor as Director

5 October 2007

Appointed Nicolson, Sean Torquil as Secretary

5 October 2007

Resigned Dawes, Christopher Charles Roland as Secretary

1 January 2007

Appointed Dawes, Christopher Charles Roland as Secretary

31 December 2006

Resigned The City Partnership (UK) Ltd as Corporate Secretary

5 August 2005

Appointed The City Partnership (UK) Ltd as Corporate Secretary

5 August 2005

Resigned Andras, Peter Emil, Dr as Secretary

11 May 2005

Appointed Drucker, Royston Frederick, Dr as Director

1 January 2005

Appointed Cordiner, Johnny Mark as Director

5 October 2004

Resigned Howse, Nicholas Alan as Secretary

5 October 2004

Appointed Andras, Peter Emil, Dr as Secretary

8 November 2001

Appointed Howse, Nicholas Alan as Secretary

8 November 2001

Appointed Young, Malcolm Philip as Director

8 November 2001

Resigned Dickinson Dees as Corporate Nominee Secretary

8 November 2001

Resigned Care, Timothy James as Nominee Director

15 October 2001

Appointed Dickinson Dees as Corporate Nominee Secretary

15 October 2001

Appointed Care, Timothy James as Nominee Director

Ownership 0 active

People and entities with significant control, from the Companies House PSC register

The company has declared that it has no person with significant control.

Former controllers (1)

28 October 2019

Ceased Invesco Ltd — Owns 25–50% of shares

Filings 259

Date	Description	Made Up To
27 October 2026	Confirmation statement with updates	15 October 2026
26 October 2026	Register inspection address has been changed
14 October 2026	Appointment of a director
14 August 2026	Full accounts	31 January 2026
20 June 2026	Statement of capital following an allotment of shares