Website & contact details
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- The site of this company’s group or brand.
Astex Therapeutics Limited
- Incorporated
- 14 April 1999 (27 years)
- Industry
- Research and experimental development on biotechnology (72110)
- Directors
- John Edward KrausYoshihisa YamadaMichelle Ann Jones
- Owned by
- Otsuka America Inc
- Accounts type
- Full
- Region
- East of England
- Address
- 436 Cambridge Science ParkMilton RoadCambridgeCB4 0QA
Filing status
- Accounts due
- 30 September 2027
- Last accounts
- 31 December 2025
- Conf. stmt due
- 16 May 2027
- Last conf. stmt
- 2 May 2026
Charges
- Total
- 2
- Outstanding
- 0
- Part satisfied
- 0
- Satisfied
- 2
Officers 7 active
Officer details are public data from the Companies House register.
Kraus, John Edward
Director · Appointed 1 April 2026
American
Born December 1966 (59)
Yamada, Yoshihisa
Director · Appointed 1 April 2026
Japanese
Born January 1967 (59)
Jones, Michelle Ann, Dr
Director · Appointed 1 October 2025
British
Born February 1974 (52)
Pereira, Brian Jude Gerard, Dr
Director · Appointed 1 March 2025
American
Born October 1958 (68)
Shiratsuchi, Takayuki, Dr
Director · Appointed 1 March 2025
Japanese
Born October 1969 (57)
Director · Appointed 1 March 2025
British,Italian
Born November 1956
Jones, Neil Steven
Secretary · Appointed 29 June 2000
British
Officer history (35 former)
1 April 2026
Appointed Yamada, Yoshihisa as Director
1 April 2026
Appointed Kraus, John Edward as Director
31 March 2026
Resigned Nakamura, Tsuyoshi as Director
31 March 2026
Resigned Mcquade, Robert Dwyer, Dr. as Director
1 October 2025
Appointed Jones, Michelle Ann, Dr as Director
1 October 2025
Appointed Nakamura, Tsuyoshi as Director
30 September 2025
30 September 2025
1 March 2025
Appointed Pereira, Brian Jude Gerard, Dr as Director
1 March 2025
Resigned Kurogi, Yasuhisa, Dr as Director
1 March 2025
1 March 2025
Appointed Shiratsuchi, Takayuki, Dr as Director
1 March 2025
1 March 2024
Appointed Kurogi, Yasuhisa, Dr as Director
1 March 2024
Resigned Gehrke, Michael Edward as Director
1 March 2023
Appointed Gehrke, Michael Edward as Director
11 April 2022
Resigned Azab, Mohammad, Dr. as Director
31 December 2020
Resigned Bodnar, Andrew, Dr as Director
23 May 2015
1 January 2014
Resigned Molkentin, Michael as Director
1 January 2014
Appointed Azab, Mohammad, Dr. as Director
1 January 2014
1 January 2014
Appointed Bodnar, Andrew, Dr as Director
1 January 2014
Appointed Mcquade, Robert Dwyer, Dr. as Director
1 January 2014
Resigned Buckland, Robert Martin, Dr as Director
1 January 2014
Resigned Manuso, James S J, Dr as Director
20 July 2011
Resigned Oliver De Vezin, Edmund Martin as Director
20 July 2011
Resigned Van Beneden, Patrick as Director
20 July 2011
Resigned Kola, Ismail, Dr as Director
20 July 2011
20 July 2011
Appointed Molkentin, Michael as Director
20 July 2011
20 July 2011
Appointed Manuso, James S J, Dr as Director
20 July 2011
20 July 2011
Resigned Ringrose, Peter Stuart, Dr as Director
20 July 2011
11 May 2010
1 May 2010
Appointed Kola, Ismail, Dr as Director
30 April 2010
15 September 2009
Appointed Oliver De Vezin, Edmund Martin as Director
23 July 2009
17 July 2008
Appointed Buckland, Robert Martin, Dr as Director
16 January 2008
Resigned Bushara, Leon Ramsey as Director
30 April 2007
13 July 2006
13 July 2006
Appointed Bushara, Leon Ramsey as Director
1 January 2005
Appointed Ringrose, Peter Stuart, Dr as Director
9 June 2004
10 December 2003
27 March 2002
27 March 2002
10 December 2001
18 May 2001
Resigned Olivier De Vezin, Edmund Martin as Director
18 May 2001
24 April 2001
Appointed Van Beneden, Patrick as Director
29 June 2000
Appointed Jones, Neil Steven as Secretary
29 June 2000
29 June 2000
29 June 2000
29 June 2000
29 June 2000
29 February 2000
29 February 2000
19 October 1999
Appointed Olivier De Vezin, Edmund Martin as Director
18 May 1999
18 May 1999
18 May 1999
18 May 1999
18 May 1999
18 May 1999
18 May 1999
18 May 1999
18 May 1999
18 May 1999
14 April 1999
14 April 1999
14 April 1999
Ownership 1 active
People and entities with significant control, from the Companies House PSC register
Otsuka America Inc
Corporate entity · Notified 6 April 2016
Owns 75–100% of shares
Holds 75–100% of voting rights
Right to appoint and remove directors
Us Corporation
Reg. no. 2199821
Financials
Balance sheet as at 31 December 2025 · full accounts
- Net Assets
- £163,640,229
- Profit
- £283,380,911
- Return on Equity
- 173%
Trend
Net Assets
Balance sheet detail
| 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | |
|---|---|---|---|---|---|---|
| Fixed Assets | £21,512,628 | £46,839,382 | ||||
| Current Assets | £177,761,391 | £208,383,301 | £138,795,915 | £58,591,191 | ||
| Debtors | £22,998,334 | |||||
| Cash | £75,794,372 | £32,385,438 | ||||
| Creditors (< 1 year) | £9,565,823 | |||||
| Net Assets | £163,640,229 | £200,259,318 | £136,032,406 | £89,032,093 | £73,305,736 | |
| Shareholder Funds | £163,640,229 | £200,259,318 | £136,032,406 | £89,032,093 | £73,305,736 | |
| Turnover | £276,803,907 | £202,455,603 | £117,178,479 | £92,355,171 | ||
| Cost of Sales | £54,623,242 | |||||
| Admin Expenses | £16,744,441 | £11,374,340 | £6,381,929 | £4,780,566 | £4,896,461 | |
| Operating Profit | £339,607,762 | £217,672,176 | £138,705,487 | £69,063,399 | £45,518,901 | |
| Profit Before Tax | £136,566,115 | £45,701,138 | ||||
| Tax | £14,565,802 | £5,833,480 | ||||
| Profit for Period | £283,380,911 | £189,226,912 | £122,000,313 | £65,726,357 | £39,867,658 | £29,862,670 |
Filings
Recent filings only. See the full history on Companies House
| Date | Description | Made Up To | Pages | |
|---|---|---|---|---|
| 30 July 2026 | Confirmation statement with no updates | 2 May 2026 | 3 | |
| 28 July 2026 | Appointment of a director | 2 | ||
| 28 July 2026 | Appointment of a director | 2 | ||
| 26 July 2026 | Termination of appointment of a director | 1 | ||
| 26 July 2026 | Termination of appointment of a director | 1 |
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