Silence Therapeutics PLC

Active02992058 Public limited company
Incorporated
18 November 1994 (31 years)
Previously known as
SR Pharma PLC (until 26 April 2007)
Stanford Rook Holdings PLC (until 21 June 1999)
Industry
Research and experimental development on biotechnology (72110)
Directors
Rhonda Hellums
James Lawrence Ede-Golightly
Tim Mcinerney
Accounts type
Group
Region
Greater London
Address
5 Brayford Square
London
E1 0SG

Filing status

Accounts due
30 June 2027
Last accounts
31 December 2025
Conf. stmt due
19 August 2027
Last conf. stmt
5 August 2026

Charges

Total
1
Outstanding
0
Part satisfied
0
Satisfied
1

Officers 6 active

Officer details are public data from the Companies House register.

Hellums, Rhonda
Director · Appointed 18 December 2025
American
Born December 1971 (54)
Ede-Golightly, James Lawrence
Director · Appointed 14 December 2025
British
Born August 1979 (47)
Mcinerney, Tim
Director · Appointed 5 May 2025
American
Born October 1960 (66)
Hellums, Rhonda
Secretary · Appointed 26 January 2024
Director · Appointed 25 April 2019
Also at Tern PLC · more companies
British
Born January 1954 (72)
Lemus, Dave
Director · Appointed 21 June 2018
American
Born October 1962 (64)
Officer history (61 former)
18 December 2025
Appointed Hellums, Rhonda as Director
14 December 2025
Appointed Ede-Golightly, James Lawrence as Director
14 December 2025
Resigned Tooman, Craig as Director
11 August 2025
Resigned Davidson, Michael, Dr. as Director
26 June 2025
Resigned Ede-Golightly, James Lawrence as Director
5 May 2025
Appointed Mcinerney, Tim as Director
30 April 2024
Resigned Gray, Alistair William as Director
26 January 2024
Appointed Hellums, Rhonda as Secretary
22 December 2023
Resigned Murphy, Sarah as Secretary
1 July 2023
Resigned Campion, Giles Victor, Dr as Director
1 April 2023
Resigned Romano, Steven, Dr as Director
28 September 2022
Resigned Ruskin, Barbara, Dr. as Secretary
28 September 2022
Appointed Murphy, Sarah as Secretary
22 February 2022
Resigned Rothera, Mark as Director
22 February 2022
Appointed Tooman, Craig as Director
6 January 2021
Appointed Davidson, Michael, Dr. as Director
1 December 2020
Appointed Ruskin, Barbara, Dr. as Secretary
1 December 2020
Resigned Quinn, Robert, Dr as Secretary
14 September 2020
Appointed Rothera, Mark as Director
9 June 2020
Resigned Campion, Giles Victor, Dr as Director
9 June 2020
Appointed Campion, Giles Victor, Dr as Director
19 May 2020
Appointed Campion, Giles Victor, Dr as Director
17 December 2019
Resigned Solomon, David Horn, Dr as Director
29 July 2019
Appointed Romano, Steven, Dr as Director
25 April 2019
Resigned Parker, Stephen Barry, Dr as Director
25 April 2019
Appointed Ede-Golightly, James Lawrence as Director
25 April 2019
Appointed Ross, Iain Gladstone as Director
16 April 2019
Resigned Richards, Andrew John Mcglashan, Dr as Director
9 January 2019
Appointed Quinn, Robert, Dr as Secretary
9 January 2019
Resigned Ellam, David John as Director
9 January 2019
Resigned Ellam, David John as Secretary
20 August 2018
Resigned Jenkins, Annalisa as Director
17 July 2018
Appointed Solomon, David Horn, Dr as Director
21 June 2018
Appointed Lemus, Dave as Director
4 June 2018
Resigned Mortazavi, Ali as Director
16 October 2017
Appointed Jenkins, Annalisa as Director
14 September 2016
Appointed Richards, Andrew John Mcglashan, Dr as Director
19 July 2016
Resigned Freeborn, Tim as Secretary
18 July 2016
Appointed Ellam, David John as Secretary
18 July 2016
Appointed Ellam, David John as Director
17 June 2016
17 June 2016
Resigned Khan, Michael Mohamed Tarik, Dr as Director
5 April 2016
Resigned Collinson, Stuart John Myles, Dr as Director
5 April 2016
Resigned Karlsson, Lars Georg Emanuel as Director
18 January 2016
Appointed Collinson, Stuart John Myles, Dr as Director
18 January 2016
Resigned Sturge, Simon John as Director
12 November 2015
Appointed Gray, Alistair William as Director
22 September 2015
Resigned Riddell, Alastair James, Dr as Director
8 January 2015
Appointed Karlsson, Lars Georg Emanuel as Director
2 September 2014
Resigned Cheng, Annie as Director
18 November 2013
Appointed Parker, Stephen Barry, Dr as Director
18 November 2013
Resigned Randall, Jeremy Anthony Philip as Director
18 November 2013
Appointed Riddell, Alastair James, Dr as Director
21 August 2013
Appointed Sturge, Simon John as Director
26 June 2013
Resigned Mack, David as Director
30 May 2013
Appointed Cheng, Annie as Director
8 October 2012
Appointed Freeborn, Timothy Charles Adrian as Director
18 September 2012
Appointed Khan, Michael Mohamed Tarik, Dr as Director
2 August 2012
Resigned Herrmann, Max Stephen as Director
2 August 2012
Appointed Mortazavi, Ali as Director
2 August 2012
Resigned Clancy, Annette as Director
2 August 2012
Appointed Freeborn, Tim as Secretary
2 August 2012
Resigned Sedgwick, Anthony, Dr as Director
2 August 2012
Resigned Herrmann, Max Stephen as Secretary
9 February 2012
Appointed Sedgwick, Anthony, Dr as Director
9 February 2012
Resigned Christely, Thomas as Director
31 December 2011
Resigned U'Prichard, David Charles, Dr as Director
19 September 2011
Appointed Christely, Thomas as Director
1 August 2011
Resigned Haworth, Philip as Director
29 July 2011
Resigned Topper, James as Director
14 May 2010
Appointed Herrmann, Max Stephen as Director
14 May 2010
Appointed Herrmann, Max Stephen as Secretary
27 February 2010
Resigned Davies, Jon Melvyn as Secretary
27 February 2010
Resigned Davies, Jon Melvyn as Director
27 February 2010
Resigned Ross, Iain Gladstone as Director
5 January 2010
Appointed Mack, David as Director
5 January 2010
Resigned Reynolds, Hugh Ronald Peter as Director
5 January 2010
Appointed Topper, James as Director
5 January 2010
Resigned Curnock Cook, Jeremy Lawrence as Director
5 January 2010
Appointed Haworth, Philip as Director
5 January 2010
Resigned Wetzel, Bernd Otto, Dr as Director
17 July 2008
Resigned Vick, Jeffery Scott as Director
1 July 2008
Appointed Randall, Jeremy Anthony Philip as Director
1 July 2008
Resigned Rugheimer, Iain Nils Hessey as Director
1 July 2008
Appointed Clancy, Annette as Director
27 July 2007
Appointed Vick, Jeffery Scott as Director
11 July 2005
Appointed U'Prichard, David Charles, Dr as Director
11 July 2005
Appointed Wetzel, Bernd Otto, Dr as Director
11 July 2005
Appointed Curnock Cook, Jeremy Lawrence as Director
18 June 2004
Resigned Hill, David as Director
28 May 2004
Appointed Ross, Iain Gladstone as Director
20 May 2004
Resigned Boyle, Eric James as Director
20 May 2004
Appointed Reynolds, Hugh Ronald Peter as Director
20 May 2004
Resigned Lambert, John Anthony as Director
20 July 2003
Resigned Chard, Timothy as Director
17 July 2003
Resigned Kennard, David Anthony, Dr as Director
19 May 2003
Appointed Hill, David as Director
4 March 2003
Resigned Ross, Iain Gladstone as Director
7 January 2003
Appointed Ross, Iain Gladstone as Director
22 May 2002
Resigned Geddes, Duncan, Prof as Director
21 May 2002
Resigned Lang, Thomas, Dr as Director
27 September 2001
Resigned Stanford, John Lawson, Dr as Director
27 September 2001
18 September 2000
Appointed Lambert, John Anthony as Director
21 August 2000
Appointed Geddes, Duncan, Prof as Director
31 August 1999
Resigned Pattison, John, Professor as Director
25 March 1998
Resigned Stanford, Cynthia Ann as Director
25 March 1998
Resigned Warren, Simon Oliver Henry as Director
10 February 1998
Appointed Lang, Thomas, Dr as Director
12 May 1997
Appointed Kennard, David Anthony, Dr as Director
21 February 1997
Appointed Chard, Timothy as Director
1 March 1995
Resigned Carswell, John Wilson as Director
19 December 1994
Appointed Rugheimer, Iain Nils Hessey as Director
18 November 1994
Appointed Pattison, John, Professor as Director
18 November 1994
Appointed Stanford, John Lawson, Dr as Director
18 November 1994
Appointed Stanford, Cynthia Ann as Director
18 November 1994
Appointed Temple Secretaries Limited as Corporate Nominee Secretary
18 November 1994
Appointed Carswell, John Wilson as Director
18 November 1994
18 November 1994
Resigned Temple Secretaries Limited as Corporate Nominee Director
18 November 1994
Appointed Warren, Simon Oliver Henry as Director
18 November 1994
Appointed Temple Secretaries Limited as Corporate Nominee Director
18 November 1994
Appointed Boyle, Eric James as Director
18 November 1994
Resigned Company Directors Limited as Corporate Nominee Director
18 November 1994
Appointed Davies, Jon Melvyn as Secretary
18 November 1994
Appointed Company Directors Limited as Corporate Nominee Director
18 November 1994
Appointed Davies, Jon Melvyn as Director
18 November 1994
Resigned Temple Secretaries Limited as Corporate Nominee Secretary

Ownership 0 active

People and entities with significant control, from the Companies House PSC register

Holdings 2

Companies where Silence Therapeutics PLC is registered as a person with significant control

Owns 75–100% of shares
Proposed for strike-off
Proposed for strike-off
Former controllers (2)
10 August 2026
Ceased Richard Ian Griffiths — Owns 25–50% of shares
30 November 2021
Ceased Richard Ian Griffiths — Owns 25–50% of shares (as a firm)

Filings

Recent filings only. See the full history on Companies House

DateDescriptionMade Up ToPagesPDF
5 November 2026Registered office address changed—
2 November 2026Confirmation statement with updates5 August 2026
28 August 2026Statement of capital following an allotment of shares
18 August 2026Cessation of a person with significant control
21 June 2026Group of companies' accounts31 December 2025
Show all recent filings

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